Nexium users, especially those taking Nexium for over 1 year or in high doses, have reported some of the following side effects:

 

• Abdominal Pain

• Headache

• Liver Failure

• Fast Heartbeat

• Unusual Bleeding

• Hip Fractures

• Spine Fractures

• Wrist Fractures

• Decreased Bone Density

The risk of the side effects while taking Nexium is greatly increased in patients receiving high doses or in those who have been taking Nexium for longer than 1 year. In 2011, the FDA updated their initial warning after it had determined that the use of high doses of Proton Pump Inhibitors for more than a year can increase the risk of osteoporosis and fractures of the hip, wrist and spine.